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Belda, Eugeni [Author]; Voland, Lise [Author]; Tremaroli, Valentina [Author]; Falony, Gwen [Author]; Adriouch, Solia [Author]; Assmann, Karen E. [Author]; Prifti, Edi [Author]; Aron-Wisnewsky, Judith [Author]; Debédat, Jean [Author]; Le Roy, Tiphaine [Author]; Nielsen, Trine [Author]; Amouya, Chloé [Author]; André, Sébastien [Author]; Andreelli,, Fabrizio [Author]; Blüher, Matthias Blüher, [Author]; Chakaroun, Rima [Author]; Chilloux, Julien [Author]; Coelho, Luis Pedro [Author]; Dao, Maria Carlota [Author]; Das, Promi [Author]; Fellahi, Soraya [Author]; Forslund, Sofia [Author]; Galleron, Nathalie [Author]; Hansen, Tue [Author]; [...]

Impairment of gut microbial biotin metabolism and host biotin status in severe obesity

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  • Media type: E-Article
  • Title: Impairment of gut microbial biotin metabolism and host biotin status in severe obesity : effect of biotin and prebiotic supplementation on improved metabolism
  • Contributor: Belda, Eugeni [Author]; Voland, Lise [Author]; Tremaroli, Valentina [Author]; Falony, Gwen [Author]; Adriouch, Solia [Author]; Assmann, Karen E. [Author]; Prifti, Edi [Author]; Aron-Wisnewsky, Judith [Author]; Debédat, Jean [Author]; Le Roy, Tiphaine [Author]; Nielsen, Trine [Author]; Amouya, Chloé [Author]; André, Sébastien [Author]; Andreelli,, Fabrizio [Author]; Blüher, Matthias Blüher, [Author]; Chakaroun, Rima [Author]; Chilloux, Julien [Author]; Coelho, Luis Pedro [Author]; Dao, Maria Carlota [Author]; Das, Promi [Author]; Fellahi, Soraya [Author]; Forslund, Sofia [Author]; Galleron, Nathalie [Author]; Hansen, Tue [Author]; [...]
  • Published: London: BMJ Publishing Group, [2024]
  • Published in: Gut ; 71,12 (2022), Seite 2463-2480
  • Language: English
  • DOI: 10.1136/gutjnl-2021-325753
  • Keywords: biotin metabolism ; biotin status ; prebiotic supplementation
  • Origination:
  • Footnote:
  • Description: Gut microbiota is a key component in obesity and type 2 diabetes, yet mechanisms and metabolites central to this interaction remain unclear. We examined the human gut microbiome’s functional composition in healthy metabolic state and the most severe states of obesity and type 2 diabetes within the MetaCardis cohort. We focused on the role of B vitamins and B7/B8 biotin for regulation of host metabolic state, as these vitamins influence both microbial function and host metabolism and inflammation.
  • Access State: Open Access
  • Rights information: Attribution (CC BY)