Hambach, Lothar;
Heil, Gerhard;
Hertenstein, Bernd;
Ganser, Arnold
Persistent aplasia after chemotherapy for acute myeloid leukaemia treated with stem cell transplantation from a matched unrelated donor after dose‐reduced conditioning
You can manage bookmarks using lists, please log in to your user account for this.
Media type:
E-Article
Title:
Persistent aplasia after chemotherapy for acute myeloid leukaemia treated with stem cell transplantation from a matched unrelated donor after dose‐reduced conditioning
Contributor:
Hambach, Lothar;
Heil, Gerhard;
Hertenstein, Bernd;
Ganser, Arnold
Description:
<jats:p><jats:bold>Summary.</jats:bold> Persistent aplasia is a rare complication with poor prognosis after intensive chemotherapy for acute leukaemia. A 59‐year‐old man with acute myeloid leukaemia (AML), was treated after 186 d of chemotherapy‐induced persistent aplasia with an allogeneic peripheral blood stem cell transplantation (PBSCT) from a matched unrelated donor (MUD) after dose‐reduced conditioning. The patient remains in complete haematological remission more than 8·5 months after haematological recovery. We believe that this is the first reported case of treatment for chemotherapy‐induced persistent aplasia with MUD‐PBSCT after dose‐reduced conditioning, a procedure that can be successfully performed even in elderly patients.</jats:p>