• Media type: E-Article
  • Title: Reactive Thrombocytosis in Non-aneurysmal Subarachnoid Hemorrhage
  • Contributor: Dubinski, Daniel; Won, Sae-Yeon; Behmanesh, Bedjan; Brawanski, Nina; Seifert, Volker; Senft, Christian; Konczalla, Juergen
  • Published: Georg Thieme Verlag KG, 2020
  • Published in: Journal of Neurological Surgery Part A: Central European Neurosurgery, 81 (2020) 5, Seite 412-417
  • Language: English
  • DOI: 10.1055/s-0040-1709167
  • ISSN: 2193-6315; 2193-6323
  • Keywords: Neurology (clinical) ; Surgery
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:p> Background The role of reactive thrombocytosis in non-aneurysmal subarachnoid hemorrhage (NA-SAH) is largely unexplored to date. Therefore, the impact of a quantitative thrombocyte dynamic in patients with NA-SAH and its clinical relevance were analyzed in the present study.</jats:p><jats:p> Methods In this retrospective analysis, 113 patients with nontraumatic and NA-SAH treated between 2003 and 2015 at our institution were included. World Federation of Neurosurgical Societies admission status, cerebral vasospasm, delayed infarction, hydrocephalus, need for ventriculoperitoneal (VP) shunt, and Fisher grade were analyzed for their association with reactive thrombocytosis.</jats:p><jats:p> Results Reactive thrombocytosis was not associated with hydrocephalus (p ≥ 0.05), need for VP shunt implantation (p ≥ 0.05), cerebral vasospasm (p ≥ 0.05), or delayed cerebral ischemia (p ≥ 0.05).</jats:p><jats:p> Conclusion Our study is the first to investigate the role of thrombocyte dynamics, reactive thrombocytosis, and the clinical course of NA-SAH patients. Our analysis showed no significant impact of thrombocyte count on NA-SAH sequelae.</jats:p>