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Media type:
E-Article
Title:
Natural language indicators of differential gene regulation in the human immune system
Contributor:
Mehl, Matthias R.;
Raison, Charles L.;
Pace, Thaddeus W. W.;
Arevalo, Jesusa M. G.;
Cole, Steve W.
imprint:
Proceedings of the National Academy of Sciences, 2017
Published in:Proceedings of the National Academy of Sciences
Language:
English
DOI:
10.1073/pnas.1707373114
ISSN:
0027-8424;
1091-6490
Origination:
Footnote:
Description:
<jats:title>Significance</jats:title>
<jats:p>Social genomics research has identified a conserved transcriptional response to adversity (CTRA) that may contribute to social disparities in health. This study identified systematic individual differences in natural language use that track CTRA gene expression more closely than do conventional self-report measures of stress, anxiety, or depression. These language style markers may provide a useful behavioral indicator of the neurobiological processes that mediate social influences on gene expression in immune cells.</jats:p>