Description:
<jats:title>Abstract</jats:title><jats:p><jats:italic>Background</jats:italic>. Activin A and inhibin A have been found to be elevated in women without diabetes subsequently developing pre‐eclampsia. The aim was to investigate whether activin A and inhibin A in serum were elevated in type I diabetic women after developing pre‐eclampsia and, if so, were they clinically useful as predictors of pre‐eclampsia. <jats:italic>Methods</jats:italic>. In a prospective study, maternal serum was analyzed for activin A and inhibin A in 115 women with type 1 diabetes at 10, 14, 22, 28, and 33 weeks of gestation. <jats:italic>Results</jats:italic>. Fourteen women (12%) developed pre‐eclampsia (26–37 weeks of gestation) and 101 did not. The two groups were comparable regarding age, body mass index, and diabetes duration. There was no difference between serum concentrations of activin A and inhibin A in women developing pre‐eclampsia and women who did not at any gestational period. <jats:italic>Conclusions</jats:italic>. Serum concentrations of activin A and inhibin A could not predict pre‐eclampsia in type I diabetes.</jats:p>