• Media type: E-Article
  • Title: Goitrous congenital hypothyroidism in a twin pregnancy causing respiratory obstruction at birth: Implications for management
  • Contributor: Reynolds, Ben Christopher; Simpson, Judith Helen; Macara, Lena; Bruce Watt, Andrew James; Kubba, Haytham; Donaldson, Malcolm David Cairns; Pohlen, Joachim
  • imprint: Wiley, 2006
  • Published in: Acta Paediatrica
  • Language: English
  • DOI: 10.1080/08035250600711074
  • ISSN: 0803-5253; 1651-2227
  • Keywords: General Medicine ; Pediatrics, Perinatology and Child Health
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:p>We report a twin pregnancy complicated by fetal goitrous hypothyroidism secondary to dyshormonogenesis caused by thyroglobulin deficiency. Antenatal treatment with intra‐amniotic thyroxine was considered but not performed, given the late gestational age at diagnosis and the multiple nature of the pregnancy. Both twins developed airway obstruction at delivery, requiring intubation and ventilation. We review the literature and describe the practical issues relating to the antenatal assessment and perinatal management of fetal goitre.</jats:p>