• Media type: E-Article
  • Title: RECIPROCAL EFFECTS OF CONCOMITANT INFECTIONS
  • Contributor: Pearce, Louise
  • imprint: Rockefeller University Press, 1928
  • Published in: Journal of Experimental Medicine
  • Language: English
  • DOI: 10.1084/jem.48.3.363
  • ISSN: 0022-1007; 1540-9538
  • Keywords: Immunology ; Immunology and Allergy
  • Origination:
  • Footnote:
  • Description: <jats:p>An experiment is reported in which was studied the effects of a concomitant vaccinal infection and of vaccinal immunity upon the reaction to syphilis in rabbits induced by intracutaneous inoculation.</jats:p> <jats:p>The results obtained showed that the reaction was modified by both conditions. A vaccinal infection initiated at the time of syphilitic inoculation was associated with a defensive reaction of lessened efficiency, the ensuing syphilis being more severe than in control animals. A state of vaccinal immunity present at the time of syphilitic inoculation was associated with a reaction of heightened efficiency, the ensuing syphilis being very mild.</jats:p> <jats:p>These results are in harmony with those obtained in other experiments in which the intratesticular route of syphilitic inoculation was employed.</jats:p>
  • Access State: Open Access