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Media type:
E-Article
Title:
High-throughput gene screen reveals modulators of nuclear shape
Contributor:
Tamashunas, Andrew C.;
Tocco, Vincent J.;
Matthews, James;
Zhang, Qiao;
Atanasova, Kalina R.;
Paschall, Lauren;
Pathak, Shreya;
Ratnayake, Ranjala;
Stephens, Andrew D.;
Luesch, Hendrik;
Licht, Jonathan D.;
Lele, Tanmay P.
imprint:
American Society for Cell Biology (ASCB), 2020
Published in:Molecular Biology of the Cell
Language:
English
DOI:
10.1091/mbc.e19-09-0520
ISSN:
1059-1524;
1939-4586
Origination:
Footnote:
Description:
<jats:p> Using a high-throughput RNAi screen of epigenetic regulators combined with an automated elliptical Fourier analysis, we identify genes required for the maintenance of nuclear shape in breast epithelial cells. </jats:p>