Description:
<jats:title>Abstract</jats:title><jats:p>Summary: PfamAlyzer is a Java applet that enables exploration of Pfam domain architectures using a user-friendly graphical interface. It can search the UniProt protein database for a domain pattern. Domain patterns similar to the query are presented graphically by PfamAlyzer either in a ranked list or pinned to the tree of life. Such domain-centric homology search can assist identification of distant homologs with shared domain architecture.</jats:p><jats:p>Availability: PfamAlyzer has been integrated with the Pfam database and can be accessed at http://pfam.cgb.ki.se/pfamalyzer.</jats:p><jats:p>Contact: Erik.Sonnhammer@ki.se</jats:p>