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Zaborowski, Alexandra M; Abdile, Ahmed; Adamina, Michel; Aigner, Felix; d'Allens, Laura; Allmer, Caterina; Álvarez, Andrea; Anula, Rocio; Andric, Mihailo; Atallah, Sam; Bach, Simon; Bala, Miklosh; Barussaud, Marie; Bausys, Augustinas; Beggs, Andrew; Bellolio, Felipe; Bennett, Melissa-Rose; Berdinskikh, Anton; Bevan, Vicki; Biondo, Sebastiano; Bislenghi, Gabriele; Bludau, Marc; Brouwer, Nelleke; Brown, Carl; [...]

Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response

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  • Media type: E-Article
  • Title: Microsatellite instability in young patients with rectal cancer: molecular findings and treatment response
  • Contributor: Zaborowski, Alexandra M; Abdile, Ahmed; Adamina, Michel; Aigner, Felix; d'Allens, Laura; Allmer, Caterina; Álvarez, Andrea; Anula, Rocio; Andric, Mihailo; Atallah, Sam; Bach, Simon; Bala, Miklosh; Barussaud, Marie; Bausys, Augustinas; Beggs, Andrew; Bellolio, Felipe; Bennett, Melissa-Rose; Berdinskikh, Anton; Bevan, Vicki; Biondo, Sebastiano; Bislenghi, Gabriele; Bludau, Marc; Brouwer, Nelleke; Brown, Carl; [...]
  • imprint: Oxford University Press (OUP), 2022
  • Published in: British Journal of Surgery
  • Language: English
  • DOI: 10.1093/bjs/znab437
  • ISSN: 0007-1323; 1365-2168
  • Keywords: Surgery
  • Origination:
  • Footnote:
  • Description: <jats:p>In this study of 400 patients with early-onset rectal cancer, 12.5 per cent demonstrated microsatellite instability (MSI). MSI was associated with a reduced likelihood of nodal positivity, an increased rate of pathological complete response, and improved disease-specific survival.</jats:p>