• Media type: E-Article
  • Title: Non-motor outcomes depend on location of neurostimulation in Parkinson’s disease
  • Contributor: Petry-Schmelzer, Jan Niklas; Krause, Max; Dembek, Till A; Horn, Andreas; Evans, Julian; Ashkan, Keyoumars; Rizos, Alexandra; Silverdale, Monty; Schumacher, Wibke; Sack, Carolin; Loehrer, Philipp A; Fink, Gereon R; Fonoff, Erich T; Martinez-Martin, Pablo; Antonini, Angelo; Barbe, Michael T; Visser-Vandewalle, Veerle; Ray-Chaudhuri, K; Timmermann, Lars; Dafsari, Haidar S; Ray-Chaudhuri, Kallol; Antonini, Angelo; Martinez-Martin, Pablo; Odin, Per; [...]
  • imprint: Oxford University Press (OUP), 2019
  • Published in: Brain
  • Language: English
  • DOI: 10.1093/brain/awz285
  • ISSN: 0006-8950; 1460-2156
  • Origination:
  • Footnote:
  • Description: <jats:p>Deep brain stimulation of the subthalamic nucleus improves non-motor symptoms in Parkinson’s disease, but with considerable inter-individual variability. Petry-Schmelzer et al. show that neurostimulation in specific subregions of the subthalamic nucleus has differential effects on mood/apathy, attention/memory and sleep-related outcomes. Neurostimulation could thus be tailored to patients’ individual non-motor profiles.</jats:p>
  • Access State: Open Access