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Galang, Romeo R; Newton, Suzanne M; Woodworth, Kate R; Griffin, Isabel; Oduyebo, Titilope; Sancken, Christina L; Olsen, Emily O’Malley; Aveni, Kathryn; Wingate, Heather; Shephard, Hanna; Fussman, Chris; Alaali, Zahra S; Silcox, Kristin; Siebman, Samantha; Halai, Umme-Aiman; Lopez, Camille Delgado; Lush, Mamie; Sokale, Ayomide; Barton, Jerusha; Chaudhary, Ifrah; Patrick, Paul H; Schlosser, Levi; Reynolds, Bethany; Gaarenstroom, Nicole; [...]

Risk Factors for Illness Severity Among Pregnant Women With Confirmed Severe Acute Respiratory Syndrome Coronavirus 2 Infection—Surveillance for Emerging Threats to Mothers and Babies Network, 22 State, Local, and Territorial Health Departments, 29 March 2020–5 March 2021

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  • Media type: E-Article
  • Title: Risk Factors for Illness Severity Among Pregnant Women With Confirmed Severe Acute Respiratory Syndrome Coronavirus 2 Infection—Surveillance for Emerging Threats to Mothers and Babies Network, 22 State, Local, and Territorial Health Departments, 29 March 2020–5 March 2021
  • Contributor: Galang, Romeo R; Newton, Suzanne M; Woodworth, Kate R; Griffin, Isabel; Oduyebo, Titilope; Sancken, Christina L; Olsen, Emily O’Malley; Aveni, Kathryn; Wingate, Heather; Shephard, Hanna; Fussman, Chris; Alaali, Zahra S; Silcox, Kristin; Siebman, Samantha; Halai, Umme-Aiman; Lopez, Camille Delgado; Lush, Mamie; Sokale, Ayomide; Barton, Jerusha; Chaudhary, Ifrah; Patrick, Paul H; Schlosser, Levi; Reynolds, Bethany; Gaarenstroom, Nicole; [...]
  • imprint: Oxford University Press (OUP), 2021
  • Published in: Clinical Infectious Diseases
  • Language: English
  • DOI: 10.1093/cid/ciab432
  • ISSN: 1058-4838; 1537-6591
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title> <jats:sec> <jats:title>Background</jats:title> <jats:p>Pregnant women with coronavirus disease 2019 (COVID-19) are at increased risk for severe illness compared with nonpregnant women. Data to assess risk factors for illness severity among pregnant women with COVID-19 are limited. This study aimed to determine risk factors associated with COVID-19 illness severity among pregnant women with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>Pregnant women with SARS-CoV-2 infection confirmed by molecular testing were reported during 29 March 2020–5 March 2021 through the Surveillance for Emerging Threats to Mothers and Babies Network (SET-NET). Criteria for illness severity (asymptomatic, mild, moderate-to-severe, or critical) were adapted from National Institutes of Health and World Health Organization criteria. Crude and adjusted risk ratios for moderate-to-severe or critical COVID-19 illness were calculated for selected demographic and clinical characteristics.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>Among 7950 pregnant women with SARS-CoV-2 infection, moderate-to-severe or critical COVID-19 illness was associated with age 25 years and older, healthcare occupation, prepregnancy obesity, chronic lung disease, chronic hypertension, and pregestational diabetes mellitus. Risk of moderate-to-severe or critical illness increased with the number of underlying medical or pregnancy-related conditions.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Older age and having underlying medical conditions were associated with increased risk of moderate-to-severe or critical COVID-19 illness among pregnant women. This information might help pregnant women understand their risk for moderate-to-severe or critical COVID-19 illness and can inform targeted public health messaging.</jats:p> </jats:sec>
  • Access State: Open Access