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Ntinginya, Nyanda Elias; Bakuli, Abhishek; Mapamba, Daniel; Sabiiti, Wilber; Kibiki, Gibson; Minja, Lilian Tina; Kuchaka, Davis; Reither, Klaus; Phillips, Patrick Peter John; Boeree, Martin Johan; Gillespie, Stephen H; Hoelscher, Michael; Heinrich, Norbert

Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse

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  • Media type: E-Article
  • Title: Tuberculosis Molecular Bacterial Load Assay Reveals Early Delayed Bacterial Killing in Patients With Relapse
  • Contributor: Ntinginya, Nyanda Elias; Bakuli, Abhishek; Mapamba, Daniel; Sabiiti, Wilber; Kibiki, Gibson; Minja, Lilian Tina; Kuchaka, Davis; Reither, Klaus; Phillips, Patrick Peter John; Boeree, Martin Johan; Gillespie, Stephen H; Hoelscher, Michael; Heinrich, Norbert
  • imprint: Oxford University Press (OUP), 2023
  • Published in: Clinical Infectious Diseases
  • Language: English
  • DOI: 10.1093/cid/ciac445
  • ISSN: 1058-4838; 1537-6591
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title> <jats:p>Bacterial killing in patients with tuberculosis (TB) relapse was compared to that in patients achieving cure, measured by TB molecular bacterial load assay (TB-MBLA) or mycobacteria growth indicator tube (MGIT) time to positivity (TTP). TB-MBLA in 4 relapsed patients was significantly different compared to 132 cured patients after 2 weeks of treatment; MGIT TTP showed a significant difference from week 8.</jats:p>
  • Access State: Open Access