• Media type: E-Article
  • Title: Neutralizing Antibody Immune Correlates for a Recombinant Protein Vaccine in the COVAIL Trial
  • Contributor: Fong, Youyi; Dang, Lauren; Zhang, Bo; Fintzi, Jonathan; Chen, Shiyu; Wang, Jing; Rouphael, Nadine G; Branche, Angela R; Diemert, David J; Falsey, Ann R; Losada, Cecilia; Baden, Lindsey R; Frey, Sharon E; Whitaker, Jennifer A; Little, Susan J; Kamidani, Satoshi; Walter, Emmanuel B; Novak, Richard M; Rupp, Richard; Jackson, Lisa A; Yu, Chenchen; Magaret, Craig A; Molitor, Cindy; Borate, Bhavesh; [...]
  • Published: Oxford University Press (OUP), 2024
  • Published in: Clinical Infectious Diseases (2024)
  • Language: English
  • DOI: 10.1093/cid/ciae465
  • ISSN: 1058-4838; 1537-6591
  • Origination:
  • Footnote:
  • Description: Abstract For COVAIL recipients of a COVID-19 Sanofi booster vaccine, neutralizing antibody titers were assessed as a correlate of risk (CoR) of COVID-19. Peak and exposure-proximal titers were inverse CoRs with covariate-adjusted hazard ratios (95% confidence intervals) 0.30 (0.11, 0.78) and 0.25 (0.07, 0.85) per 10-fold increase in weighted average titer.