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Czermak, Thomas; Seitelberger, Valentina; Hagl, Christian; Samson-Himmelstjerna, Patrick-Nicolas; Groß, Sven; Sadoni, Sebastian; Heyn, Oliver; Kellnar, Antonia; Hartrampf, Bonnie; Lemmermöhle, Eric; Klier, Ina; Rehms, Raphael; Hoffmann, Sabine; Estner, Heidi L; Fichtner, Stephanie; Lackermair, Korbinian

Survival after left ventricular assist device implantation correlates with a novel device-based measure of heart rate variability: the heart rate score

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  • Media type: E-Article
  • Title: Survival after left ventricular assist device implantation correlates with a novel device-based measure of heart rate variability: the heart rate score
  • Contributor: Czermak, Thomas; Seitelberger, Valentina; Hagl, Christian; Samson-Himmelstjerna, Patrick-Nicolas; Groß, Sven; Sadoni, Sebastian; Heyn, Oliver; Kellnar, Antonia; Hartrampf, Bonnie; Lemmermöhle, Eric; Klier, Ina; Rehms, Raphael; Hoffmann, Sabine; Estner, Heidi L; Fichtner, Stephanie; Lackermair, Korbinian
  • imprint: Oxford University Press (OUP), 2021
  • Published in: Interactive CardioVascular and Thoracic Surgery
  • Language: English
  • DOI: 10.1093/icvts/ivab063
  • ISSN: 1569-9285
  • Keywords: Cardiology and Cardiovascular Medicine ; Pulmonary and Respiratory Medicine ; Surgery
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title> <jats:p /> <jats:sec> <jats:title>OBJECTIVES</jats:title> <jats:p>The heart rate score (HRS) serves as a device-based measure of impaired heart rate variability and is an independent predictor of death in patients with heart failure and a cardiac implantable electrical device. However, no data are available for predicting death from the HRS in patients with end stage heart failure and a left ventricular assist device.</jats:p> </jats:sec> <jats:sec> <jats:title>METHODS</jats:title> <jats:p>From November 2011 to July 2018, a total of 56 patients with a pre-existing cardiac implantable electrical device underwent left ventricular assist device implantation at our 2 study sites. The ventricular HRS was calculated retrospectively during the first cardiac implantable electrical device follow-up examination following the index hospitalization. Survival during follow-up was correlated with initial HRS.</jats:p> </jats:sec> <jats:sec> <jats:title>RESULTS</jats:title> <jats:p>During the follow-up period, 46.4% of the patients (n = 26) died. The median follow-up period was 33.2 months. The median HRS after the index hospitalization was 41.1 ± 21.8%. More patients with an HRS &amp;gt;65% died compared to patients with an HRS &amp;lt;30% (76.9% vs 14.4%; P = 0.007).</jats:p> </jats:sec> <jats:sec> <jats:title>CONCLUSIONS</jats:title> <jats:p>In our multicentre experience, survival of patients after an left ventricular assist device implant correlates with the HRS. After confirmation of our findings in a larger cohort, the effect of rate-responsive pacing will be within the scope of further investigation.</jats:p> </jats:sec>
  • Access State: Open Access