• Media type: E-Article
  • Title: Vitamin D (25‐OH D) Levels are Sub‐Optimal in 2‐year old Inner City New York Puerto Rican Children with a Maternal History of Allergy Sensitization and/or Asthma
  • Contributor: Fellows, Molly; Acosta, Luis M.; Divjan, Adnan; Acevedo‐Garcia, Dolores; Rogers, Christine A.; Chew, Ginger L.; Kannan, Srimathi
  • Published: Wiley, 2011
  • Published in: The FASEB Journal, 25 (2011) S1
  • Language: English
  • DOI: 10.1096/fasebj.25.1_supplement.995.1
  • ISSN: 1530-6860; 0892-6638
  • Keywords: Genetics ; Molecular Biology ; Biochemistry ; Biotechnology
  • Origination:
  • Footnote:
  • Description: In the USA, Puerto Rican (PR) children have a higher prevalence of asthma than other Latino ethnicities. The objective of the current research was to assess vitamin D biomarker status in children living in New York City (NYC: latitude 40°) that make up the NYC‐PR Asthma Biomarkers Cohort. Blood samples were collected at age 2 years (n=143; n=53 males and 54 females). Home/demographic characteristics and respiratory symptoms were assessed every 6 months from birth‐2 years. Serum 25(OH)D concentrations were determined using radioimmunoassay [DiaSorin Inc]. At age 2 years, the mean vitamin D concentration was 23.6 ng/mL. 33% (n=47) of the children were vitamin‐D deficient (<20 ng/mL). Of the 143 children, only 17% (n=24 children) were vitamin D‐sufficient (>30 ng/mL) and the remaining 119 children (83%) had suboptimal vit D levels (< 30 ng/mL). Vitamin D sub‐optimal biomarker status is common in this sample of 2 year old inner city children of PR ethnicity. In future research, we will examine multiple determinants associated with vitamin D deficiency and asthma morbidity markers in this sample. The NYC Puerto Rican Asthma project received funding from National Institutes of Health NIEHS R01 ES10922 and P30 ES009089