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Media type:
E-Article
Title:
Moderate caloric restriction results in significant loss of fat mass, limited decline in resting energy expenditure and preservation of fat free mass
Contributor:
Chezem, Jo Carol;
Thomas, Adrienne;
Holden, Jocelyn
Description:
The objective of this retrospective study was to describe changes in body composition and resting energy expenditure (REE) in adults enrolled in a 25‐week weight loss program that restricted caloric intake to 90% of measured REE. Data collected included total body mass (TBM), fat mass (FM) and fat‐free mass (FFM) from air displacement plethysmography; measured REE from indirect calorimetry and predicted REE from linear regression. Data from 312 clients were analyzed using hierarchical linear modeling. From baseline to week 25, there were significant declines in TBM (−8.7 kg; p < .001) and FM (−8.3 kg; p < .001). During the same time period, FFM remained unchanged (0 kg; p > .05). REE was significantly lower at weeks 13 (1580 kcal) and 25 (1592 kcal) compared to baseline (1709 kcal) (p ≤ .001); however, REE at weeks 13 and 25 were similar (p > 0.05). At weeks 13 and 25, predicted REE (1579 and 1907 kcal, respectively) was significantly higher than measured REE (1579 and 1592 kcal, respectively) (p < .001). Results of this study demonstrate that loss of FFM can be prevented and decline in REE, while not halted, can be attenuated during weight reduction with moderate caloric restriction. This study received research support from Target Metabolism, Inc.