Preoperative assessment of contrast-enhanced spectral mammography of diagnosed breast cancers after sonographic biopsy : Correlation to contrast-enhanced magnetic resonance imaging and 5-year postoperative follow-up
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Media type:
E-Article
Title:
Preoperative assessment of contrast-enhanced spectral mammography of diagnosed breast cancers after sonographic biopsy : Correlation to contrast-enhanced magnetic resonance imaging and 5-year postoperative follow-up
:
Correlation to contrast-enhanced magnetic resonance imaging and 5-year postoperative follow-up
Description:
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<jats:title>Abstract</jats:title>
<jats:p>To assess the feasibility of using contrast-enhanced spectral mammography (CESM) for operative planning of patients with breast cancers who were initially diagnosed by sonographic guided biopsy.</jats:p>
<jats:p>With the approval of the Institutional Review Board of our hospital, we retrospectively reviewed the data on patients with breast cancers who underwent CESM and contrast-enhanced magnetic resonance imaging (CE-MRI) prior to operation and were followed up for at least 5 years postoperatively. The patients with breast cancer diagnosed by sonographic guided biopsy without mammography were included for analysis. The size and number of cancers on low-energy mammograms (LE-MG), recombined subtracted mammograms (RSM), and CE-MRI were recorded and compared with microscopic histopathologic data and at least 5 years of clinical follow-up data.</jats:p>
<jats:p>Fifty-one cancerous breasts of 46 patients were included in the analysis. All the principal cancers could be detected by RSM or CE-MRI; however, only 45 were by LE-MG. The Pearson correlation coefficients for the size on microscopy were 0.44 for LE-MG, 0.77 for RSM, and 0.84 for CE-MRI (all <jats:italic toggle="yes">P</jats:italic>-values ≤.001). Regarding the microscopic reports, RSM or CE-MRI had sensitivities of 100% and a positive predictive value of 63.6% for multicentric cancers. One breast cancer with partial mastectomy recurred after 3 years of follow-up.</jats:p>
<jats:p>CESM was feasible for assessing the cancer extension and multicentric cancers as secondary examination in patients with diagnosed breast cancers after sonographic biopsy.</jats:p>
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