> Details

Moncrieft, Ashley E.; Llabre, Maria M.; McCalla, Judith Rey; Gutt, Miriam; Mendez, Armando J.; Gellman, Marc D.; Goldberg, Ronald B.; Schneiderman, Neil

Effects of a Multicomponent Life-Style Intervention on Weight, Glycemic Control, Depressive Symptoms, and Renal Function in Low-Income, Minority Patients With Type 2 Diabetes: Results of the Community Approach to Lifestyle Modification for Diabetes Randomized Controlled Trial

Reference
management

Bookmarks

Remove from
bookmarks

Share this on Whatsapp

Close

Bookmarks



You can manage bookmarks using lists, please log in to your user account for this.
  • Media type: E-Article
  • Title: Effects of a Multicomponent Life-Style Intervention on Weight, Glycemic Control, Depressive Symptoms, and Renal Function in Low-Income, Minority Patients With Type 2 Diabetes: Results of the Community Approach to Lifestyle Modification for Diabetes Randomized Controlled Trial
  • Contributor: Moncrieft, Ashley E.; Llabre, Maria M.; McCalla, Judith Rey; Gutt, Miriam; Mendez, Armando J.; Gellman, Marc D.; Goldberg, Ronald B.; Schneiderman, Neil
  • imprint: Ovid Technologies (Wolters Kluwer Health), 2016
  • Published in: Psychosomatic Medicine
  • Language: English
  • DOI: 10.1097/psy.0000000000000348
  • ISSN: 1534-7796; 0033-3174
  • Keywords: Psychiatry and Mental health ; Applied Psychology
  • Origination:
  • Footnote:
  • Description: <jats:title>ABSTRACT</jats:title> <jats:sec> <jats:title>Objective</jats:title> <jats:p>Few interventions have combined life-style and psychosocial approaches in the context of Type 2 diabetes management. The purpose of this study was to determine the effect of a multicomponent behavioral intervention on weight, glycemic control, renal function, and depressive symptoms in a sample of overweight/obese adults with Type 2 diabetes and marked depressive symptoms.</jats:p> </jats:sec> <jats:sec> <jats:title>Methods</jats:title> <jats:p>A sample of 111 adults with Type 2 diabetes were randomly assigned to a 1-year intervention (<jats:italic toggle="yes">n</jats:italic> = 57) or usual care (<jats:italic toggle="yes">n</jats:italic> = 54) in a parallel groups design. Primary outcomes included weight, glycosylated hemoglobin, and Beck Depression Inventory II score. Estimated glomerular filtration rate served as a secondary outcome. All measures were assessed at baseline and 6 and 12 months after randomization by assessors blind to randomization. Latent growth modeling was used to examine intervention effects on each outcome.</jats:p> </jats:sec> <jats:sec> <jats:title>Results</jats:title> <jats:p>The intervention resulted in decreased weight (mean [M] = 0.322 kg, standard error [SE] = 0.124 kg, <jats:italic toggle="yes">p</jats:italic> = .010) and glycosylated hemoglobin (M = 0.066%, SE = 0.028%, <jats:italic toggle="yes">p</jats:italic> = .017), and Beck Depression Inventory II scores (M = 1.009, SE = 0.226, <jats:italic toggle="yes">p</jats:italic> &lt; .001), and improved estimated glomerular filtration rate (M = 0.742 ml·min<jats:sup>−1</jats:sup>·1.73 m<jats:sup>−2</jats:sup>, SE = 0.318 ml·min<jats:sup>−1</jats:sup>·1.73 m<jats:sup>−2</jats:sup>, <jats:italic toggle="yes">p</jats:italic> = .020) each month during the first 6 months relative to usual care.</jats:p> </jats:sec> <jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Multicomponent behavioral interventions targeting weight loss and depressive symptoms as well as diet and physical activity are efficacious in the management of Type 2 diabetes.</jats:p> <jats:p> <jats:bold>Trial Registration:</jats:bold> This study is registered at Clinicaltrials.gov ID: NCT01739205.</jats:p> </jats:sec>