Media type: E-Article Title: Imaging new neurons in vivo: a pioneering tool to study the cellular biology of depression? Contributor: Römer, Benedikt; Sartorius, Alexander; Inta, Dragos; Vollmayr, Barbara; Gass, Peter Published: Wiley, 2008 Published in: BioEssays, 30 (2008) 9, Seite 806-810 Language: English DOI: 10.1002/bies.20800 ISSN: 0265-9247; 1521-1878 Keywords: General Biochemistry, Genetics and Molecular Biology Origination: Footnote: Description: AbstractHippocampal neurogenesis has been implicated in the pathogenesis of and recovery from depression. However, most of the underlying studies were endpoint investigations in experimental animals yielding conflicting results, and it has been under debate to which extent these results could be transferred to human patients. Now, researchers have developed a powerful new tool to address these questions by a non‐invasive method in humans and animals in vivo, using magnetic resonance spectroscopy to detect a biomarker for proliferating progenitor cells that give rise to new neurons.1 This makes it possible to study the role of neural progenitor cells in a wide variety of human brain disorders. BioEssays 30:806–810, 2008. © 2008 Wiley Periodicals, Inc.