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Media type:
E-Article
Title:
Generalization of monod kinetics for analysis of growth data with substrate inhibition
Contributor:
Luong, J. H. T.
Published:
Wiley, 1987
Published in:
Biotechnology and Bioengineering, 29 (1987) 2, Seite 242-248
Language:
English
DOI:
10.1002/bit.260290215
ISSN:
0006-3592;
1097-0290
Origination:
Footnote:
Description:
<jats:title>Abstract</jats:title><jats:p>The inhibitory effect of butanol on yeast growth has been studied for the strain <jats:italic>Candida utilis</jats:italic> ATCC 8205 growing aerobically on butanol under batch conditions. A mathematical expression was then proposed to fit the kinetic pattern of butanol inhibition on the specific growth rate:
<jats:disp-formula>
</jats:disp-formula></jats:p><jats:p>The maximum allowable butanol concentration above which cells do not grow was predicted to be 9.16g/L. The proposed model appears to accurately represent the experimental data obtained in this study and the literature data developed for a variety of batch culture systems at widely ranging substrate concentrations.</jats:p>