Description:
<jats:title>Abstract</jats:title><jats:p>A catalytic enantioselective approach to 4‐hydroxy‐6‐methylcyclohex‐2‐enones is presented herein. The stereogenic information is generated through a copper‐catalyzed 1,4‐addition to <jats:italic>p</jats:italic>‐benzoquinone monoketal using a chiral, BINOL‐based (BINOL = 1,1′‐bi‐2‐naphthol) phosphane ligand, according to the procedure of Feringa et al. A CBS (Corey–Bakshi–Shibata) reduction of the 1,4‐adducts gave the four possible isomers in two steps and 82–97 % <jats:italic>ee</jats:italic> (enantiomeric excess), starting from commercially available 4,4‐dimethoxycyclohexa‐2,5‐dien‐1‐one (<jats:bold>7</jats:bold>).</jats:p>