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Media type:
E-Article
Title:
Realization of noncontact confocal optical microsphere imaging microscope
Contributor:
Zhou, Yan;
Hong, Minghui
imprint:
Wiley, 2021
Published in:Microscopy Research and Technique
Language:
English
DOI:
10.1002/jemt.23793
ISSN:
1059-910X;
1097-0029
Origination:
Footnote:
Description:
<jats:title>Abstract</jats:title><jats:p>A novel noncontact confocal optical microsphere imaging microscope (COMIM) is proposed to achieve high contrast optical nano‐imaging at a high scanning speed. The developed setup obtains images with significantly higher contrast when compared with conventional bright‐field microsphere nano‐imaging, as well as with a commercial confocal laser scanning microscope (CLSM). With the image‐by‐image scanning scheme, COMIM takes only 11% time to complete a three‐dimensional (3D) scanning image than using a commercial CLSM, while still offers an outstanding resolving power for the nano‐features on the sample.</jats:p>