• Media type: E-Article
  • Title: Asymmetric synthesis of carbacyclin precursors by Pauson‐Khand cyclization
  • Contributor: Mulzer, Johann; Graske, Klaus‐Dieter; Kirste, Burkhard
  • imprint: Wiley, 1988
  • Published in: Liebigs Annalen der Chemie
  • Language: English
  • DOI: 10.1002/jlac.198819880913
  • ISSN: 0170-2041
  • Keywords: Organic Chemistry ; Physical and Theoretical Chemistry
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:p>The carbacyclin precursors <jats:bold>11, 17, 18</jats:bold> have been prepared from the en‐ynes <jats:bold>10, 15, 16</jats:bold> by cobalt‐mediated cyclization (Pauson‐Khand reaction) with varying degrees of diastereoselectivity.</jats:p>