Description:
<jats:title>Abstract</jats:title><jats:p>The Magdalena River in Colombia is one of the world's largest (discharge = 7100 m<jats:sup>3</jats:sup> s<jats:sup>−1</jats:sup>) tropical rivers, hosting > 170 aquatic vertebrate species. However, concise synthesis of the current ecological and environmental status is lacking. By documenting the anthropogenic stressors impacting the river on time scales ranging from centuries to decades, we found that the river system is subject to the compounding impacts of climate change, river impoundment, invasive alien species (IAS), catchment deforestation, and water pollution. We show that the Magdalena is a woefully understudied ecosystem relative to its critical importance to Colombia's economy, culture, and biodiversity compared with other similarly sized tropical rivers. We emphasize the need for research on (1) IAS population and ecological dynamics, (2) river damming and its links with IAS and climate change, and (3) land‐use changes as well as identifying sources of water pollution and strategies for mitigation.</jats:p>