• Media type: E-Article
  • Title: L‐asparaginase‐induced coagulopathy during therapy of acute lymphocytic leukemia
  • Contributor: Sills, Richard H.; Nelson, Douglas A.; Stockman, James A.
  • imprint: Wiley, 1978
  • Published in: Medical and Pediatric Oncology
  • Language: English
  • DOI: 10.1002/mpo.2950040406
  • ISSN: 0098-1532; 1096-911X
  • Keywords: Cancer Research ; Oncology ; Pediatrics, Perinatology and Child Health
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:p>L‐Asparaginase‐induced coagulation abnormalities were observed in all patients receiving this drug. All patients studied demonstrated low factor IX and fibrinogen levels and most (75%) had low levels of factor XI. Disturbances in other factors were much less frequent. Despite the presence of markedly abnormal coagulation studies, clinical bleeding was not observed.</jats:p>