Media type: E-Article Title: Para‐hydrogen induced polarization of Si‐29 NMR resonances as a potentially useful tool for analytical applications Contributor: Ellena, Silvano; Viale, Alessandra; Gobetto, Roberto; Aime, Silvio imprint: Wiley, 2012 Published in: Magnetic Resonance in Chemistry Language: English DOI: 10.1002/mrc.3832 ISSN: 0749-1581; 1097-458X Keywords: General Materials Science ; General Chemistry Origination: Footnote: Description: <jats:p>Para‐hydrogen–induced polarization effects have been observed in the <jats:sup>29</jats:sup>Si NMR spectra of trimethylsilyl para‐hydrogenated molecules. The high signal enhancements and the long <jats:italic>T</jats:italic><jats:sub>1</jats:sub> values observed for the <jats:sup>29</jats:sup>Si hyperpolarized resonances point toward the possibility of using <jats:sup>29</jats:sup>Si for hyperpolarization applications. A method for the discrimination of multiple compounds and/or complex mixtures of hydroxylic compounds (such as steroids), consisting of the silylization of alcoholic functionalities with an unsaturated silylalkyl moiety and subsequent reaction with para‐H<jats:sub>2</jats:sub>, is proposed. Copyright © 2012 John Wiley & Sons, Ltd.</jats:p>