Media type: E-Article Title: Mesomelic campomelia, polydactyly and Dandy–Walker cyst in siblings Contributor: Guschmann, Michael; Horn, Denise; Entezami, Michael; Urban, Maik; Hänel, Susanne; Kunze, Jürgen; Vogel, Martin imprint: Wiley, 2001 Published in: Prenatal Diagnosis Language: English DOI: 10.1002/pd.70 ISSN: 1097-0223; 0197-3851 Keywords: Genetics (clinical) ; Obstetrics and Gynecology Origination: Footnote: Description: <jats:title>Abstract</jats:title><jats:p>The present report describes two fetuses, one female and one male, with thus far undescribed skeletal malformations. The mother was a gravida 2, para 0. Both pregnancies were terminated in the second trimester because of multiple congenital anomalies diagnosed ultrasonographically resembling a short rib‐polydactyly syndrome. Both fetuses were found to have postaxial hexadactyly of the hands and feet, marked bilateral campomelia of the forearm and shank bones, and a Dandy–Walker cyst. In addition, the fourth ventricle was dilated in the first sibling and the second sibling had an inverse intestinal malrotation. A literature search failed to reveal similar observations. Copyright © 2001 John Wiley & Sons, Ltd.</jats:p>