Prevention of transmission of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum by Ixodes spp. ticks to dogs treated with the Seresto® collar (imidacloprid 10% + flumethrin 4.5%)
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Media type:
E-Article
Title:
Prevention of transmission of Borrelia burgdorferi sensu lato and Anaplasma phagocytophilum by Ixodes spp. ticks to dogs treated with the Seresto® collar (imidacloprid 10% + flumethrin 4.5%)
Published:
Springer Science and Business Media LLC, 2020
Published in:
Parasitology Research, 119 (2020) 1, Seite 299-315
Language:
English
DOI:
10.1007/s00436-019-06394-8
ISSN:
1432-1955;
0932-0113
Origination:
Footnote:
Description:
AbstractThe capability of imidacloprid 10% + flumethrin 4.5% (Seresto®) collars to prevent transmission ofBorrelia burgdorferisensu lato (Bbsl) andAnaplasma phagocytophilum(Ap) by naturally infected ticks was evaluated in two studies with 44 dogs. In each study, one group served as non-treated control, whereas the other groups were treated with the Seresto® collar. All dogs were exposed to naturallyBbsl- andAp-infected hard ticks (Ixodes ricinus,Ixodes scapularis). In study 1, tick infestation was performed on study day (SD) 63 (2 months post-treatment [p.t.]); in study 2, it was performed on SD 32 (one month p.t.) respectively SD 219 (seven months p.t.). In situ tick counts were performed 2 days after infestation. Tick counts and removals followed 6 (study 1) or 5 days (study 2) later. Blood sampling was performed for the detection of specificBbsl andApantibodies and, in study 1, for the documentation ofApDNA by PCR. Skin biopsies were examined forBbsl by PCR and culture (only study 1). The efficacy againstIxodesspp. was 100% at all time points. In study 1, two of six non-treated dogs became infected withBbsl, and four of six tested positive forAp; none of the treated dogs tested positive forBbsl orAp. In study 2, ten of ten non-treated dogs became infected withBbsl andAp; none of the treated dogs tested positive forBbsl orAp; 100% acaricidal efficacy was shown in both studies. Transmission ofBbsl andApwas successfully blocked for up to 7 months.