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Media type:
E-Article
Title:
An overview on neurobiology and therapeutics of attention-deficit/hyperactivity disorder
Contributor:
da Silva, Bruna Santos;
Grevet, Eugenio Horacio;
Silva, Luiza Carolina Fagundes;
Ramos, João Kleber Neves;
Rovaris, Diego Luiz;
Bau, Claiton Henrique Dotto
Published:
Springer Science and Business Media LLC, 2023
Published in:
Discover Mental Health, 3 (2023) 1
Language:
English
DOI:
10.1007/s44192-022-00030-1
ISSN:
2731-4383
Origination:
Footnote:
Description:
AbstractAttention-Deficit/Hyperactivity Disorder (ADHD) is a prevalent psychiatric condition characterized by developmentally inappropriate symptoms of inattention and/or hyperactivity/impulsivity, which leads to impairments in the social, academic, and professional contexts. ADHD diagnosis relies solely on clinical assessment based on symptom evaluation and is sometimes challenging due to the substantial heterogeneity of the disorder in terms of clinical and pathophysiological aspects. Despite the difficulties imposed by the high complexity of ADHD etiology, the growing body of research and technological advances provide good perspectives for understanding the neurobiology of the disorder. Such knowledge is essential to refining diagnosis and identifying new therapeutic options to optimize treatment outcomes and associated impairments, leading to improvements in all domains of patient care. This review is intended to be an updated outline that addresses the etiological and neurobiological aspects of ADHD and its treatment, considering the impact of the “omics” era on disentangling the multifactorial architecture of ADHD.