• Media type: E-Article
  • Title: Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRASG12C Inhibitor
  • Contributor: Bröker, Joachim; Waterson, Alex G.; Smethurst, Chris; Kessler, Dirk; Böttcher, Jark; Mayer, Moriz; Gmaschitz, Gerhard; Phan, Jason; Little, Andrew; Abbott, Jason R.; Sun, Qi; Gmachl, Michael; Rudolph, Dorothea; Arnhof, Heribert; Rumpel, Klaus; Savarese, Fabio; Gerstberger, Thomas; Mischerikow, Nikolai; Treu, Matthias; Herdeis, Lorenz; Wunberg, Tobias; Gollner, Andreas; Weinstabl, Harald; Mantoulidis, Andreas; [...]
  • imprint: American Chemical Society (ACS), 2022
  • Published in: Journal of Medicinal Chemistry
  • Language: English
  • DOI: 10.1021/acs.jmedchem.2c01120
  • ISSN: 0022-2623; 1520-4804
  • Origination:
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