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Souza, Renato T.;
Cecatti, Jose G.;
Pacagnella, Rodolfo C.;
Ribeiro-Do-Valle, Carolina C.;
Luz, Adriana G.;
Lajos, Giuliane J.;
Nobrega, Guilherme M.;
Griggio, Thayna B.;
Charles, Charles M.;
Bento, Silvana F.;
Silveira, Carla;
Surita, Fernanda G.;
Miele, Maria J.;
Tedesco, Ricardo P.;
Fernandes, Karayna G.;
Martins-Costa, Sérgio H. A.;
Peret, Frederico J. A.;
Feitosa, Francisco E.;
Mattar, Rosiane;
Traina, Evelyn;
Cunha Filho, Edson V.;
Vettorazzi, Janete;
Haddad, Samira M.;
Andreucci, Carla B.;
[...]
The COVID-19 pandemic in Brazilian pregnant and postpartum women: results from the REBRACO prospective cohort study
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- Media type: E-Article
- Title: The COVID-19 pandemic in Brazilian pregnant and postpartum women: results from the REBRACO prospective cohort study
- Contributor: Souza, Renato T.; Cecatti, Jose G.; Pacagnella, Rodolfo C.; Ribeiro-Do-Valle, Carolina C.; Luz, Adriana G.; Lajos, Giuliane J.; Nobrega, Guilherme M.; Griggio, Thayna B.; Charles, Charles M.; Bento, Silvana F.; Silveira, Carla; Surita, Fernanda G.; Miele, Maria J.; Tedesco, Ricardo P.; Fernandes, Karayna G.; Martins-Costa, Sérgio H. A.; Peret, Frederico J. A.; Feitosa, Francisco E.; Mattar, Rosiane; Traina, Evelyn; Cunha Filho, Edson V.; Vettorazzi, Janete; Haddad, Samira M.; Andreucci, Carla B.; [...]
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Published:
Springer Science and Business Media LLC, 2022
- Published in: Scientific Reports, 12 (2022) 1
- Language: English
- DOI: 10.1038/s41598-022-15647-z
- ISSN: 2045-2322
- Keywords: Multidisciplinary
- Origination:
- Footnote:
- Description: <jats:title>Abstract</jats:title><jats:p>Brazil presented a very high number of maternal deaths and evident delays in healthcare. We aimed at evaluating the characteristics of SARS-CoV-2 infection and associated outcomes in the obstetric population. We conducted a prospective cohort study in 15 Brazilian centers including symptomatic pregnant or postpartum women with suspected COVID-19 from Feb/2020 to Feb/2021. Women were followed from suspected infection until the end of pregnancy. We analyzed maternal characteristics and pregnancy outcomes associated with confirmed COVID-19 infection and SARS, determining unadjusted risk ratios. In total, 729 symptomatic women with suspected COVID-19 were initially included. Among those investigated for COVID-19, 51.3% (n = 289) were confirmed COVID-19 and 48% (n = 270) were negative. Initially (before May 15th), only 52.9% of the suspected cases were tested and it was the period with the highest proportion of ICU admission and maternal deaths. Non-white ethnicity (RR 1.78 [1.04–3.04]), primary schooling or less (RR 2.16 [1.21–3.87]), being overweight (RR 4.34 [1.04–19.01]) or obese (RR 6.55 [1.57–27.37]), having public prenatal care (RR 2.16 [1.01–4.68]), planned pregnancies (RR 2.09 [1.15–3.78]), onset of infection in postpartum period (RR 6.00 [1.37–26.26]), chronic hypertension (RR 2.15 [1.37–4.10]), pre-existing diabetes (RR 3.20 [1.37–7.46]), asthma (RR 2.22 [1.14–4.34]), and anaemia (RR 3.15 [1.14–8.71]) were associated with higher risk for SARS. The availability of tests and maternal outcomes varied throughout the pandemic period of the study; the beginning was the most challenging period, with worse outcomes. Socially vulnerable, postpartum and previously ill women were more likely to present SARS related to COVID-19.</jats:p>
- Access State: Open Access