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Shukla, Vivek V.; Carper, Benjamin A.; Ambalavanan, Namasivayam; Rysavy, Matthew A.; Bell, Edward F.; Das, Abhik; Patel, Ravi M.; D’Angio, Carl T.; Watterberg, Kristi L.; Cotten, C. Michael; Merhar, Stephanie L.; Wyckoff, Myra H.; Sánchez, Pablo J.; Kumbhat, Neha; Carlo, Waldemar A.; Polin, Richard A.; Laptook, Abbot R.; Keszler, Martin; Hensman, Angelita M.; Vieira, Elisa; Pierre, Lucille St.; Hibbs, Anna Maria; Walsh, Michele C.; Newman, Nancy S.; [...]

Social distancing and extremely preterm births in the initial COVID-19 pandemic period

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  • Media type: E-Article
  • Title: Social distancing and extremely preterm births in the initial COVID-19 pandemic period
  • Contributor: Shukla, Vivek V.; Carper, Benjamin A.; Ambalavanan, Namasivayam; Rysavy, Matthew A.; Bell, Edward F.; Das, Abhik; Patel, Ravi M.; D’Angio, Carl T.; Watterberg, Kristi L.; Cotten, C. Michael; Merhar, Stephanie L.; Wyckoff, Myra H.; Sánchez, Pablo J.; Kumbhat, Neha; Carlo, Waldemar A.; Polin, Richard A.; Laptook, Abbot R.; Keszler, Martin; Hensman, Angelita M.; Vieira, Elisa; Pierre, Lucille St.; Hibbs, Anna Maria; Walsh, Michele C.; Newman, Nancy S.; [...]
  • imprint: Springer Science and Business Media LLC, 2024
  • Published in: Journal of Perinatology
  • Language: English
  • DOI: 10.1038/s41372-024-01898-3
  • ISSN: 0743-8346; 1476-5543
  • Keywords: Obstetrics and Gynecology ; Pediatrics, Perinatology and Child Health
  • Origination:
  • Footnote:
  • Description: <jats:title>Abstract</jats:title><jats:sec> <jats:title>Hypothesis</jats:title> <jats:p>Increased social distancing was associated with a lower incidence of extremely preterm live births (EPLB) during the initial COVID-19 pandemic period.</jats:p> </jats:sec><jats:sec> <jats:title>Study design</jats:title> <jats:p>Prospective study at the NICHD Neonatal Research Network sites comparing EPLB (22<jats:sup>0/7</jats:sup>–28<jats:sup>6/7</jats:sup> weeks) and extremely preterm intrapartum stillbirths (EPIS) rates during the pandemic period (March-July, weeks 9–30 of 2020) with the reference period (same weeks in 2018 and 2019), correlating with state-specific social distancing index (SDI).</jats:p> </jats:sec><jats:sec> <jats:title>Results</jats:title> <jats:p>EPLB and EPIS percentages did not significantly decrease (1.58–1.45%, <jats:italic>p</jats:italic> = 0.07, and 0.08–0.06%, <jats:italic>p</jats:italic> = 0.14, respectively). SDI was not significantly correlated with percent change of EPLB (CC = 0.29, 95% CI = −0.12, 0.71) or EPIS (CC = −0.23, 95% CI = −0.65, 0.18). Percent change in mean gestational age was positively correlated with SDI (CC = 0.49, 95% CI = 0.07, 0.91).</jats:p> </jats:sec><jats:sec> <jats:title>Conclusions</jats:title> <jats:p>Increased social distancing was not associated with change in incidence of EPLB but was associated with a higher gestational age of extremely preterm births.</jats:p> </jats:sec><jats:sec> <jats:title>ClinicalTrials.gov ID</jats:title> <jats:p>Generic Database: NCT00063063.</jats:p> </jats:sec>