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Arabshahi, Homayon J.; van Rensburg, Michelle; Pilkington, Lisa I.; Jeon, Chae Yeon; Song, Mirae; Gridel, Ling-Mey; Leung, Euphemia; Barker, David; Vuica-Ross, Milena; Volcho, Konstantin P.; Zakharenko, Alexandra L.; Lavrik, Olga I.; Reynisson, Jóhannes

A synthesis, in silico, in vitro and in vivo study of thieno[2,3-b]pyridine anticancer analogues

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  • Media type: E-Article
  • Title: A synthesis, in silico, in vitro and in vivo study of thieno[2,3-b]pyridine anticancer analogues
  • Contributor: Arabshahi, Homayon J.; van Rensburg, Michelle; Pilkington, Lisa I.; Jeon, Chae Yeon; Song, Mirae; Gridel, Ling-Mey; Leung, Euphemia; Barker, David; Vuica-Ross, Milena; Volcho, Konstantin P.; Zakharenko, Alexandra L.; Lavrik, Olga I.; Reynisson, Jóhannes
  • imprint: Royal Society of Chemistry (RSC), 2015
  • Published in: MedChemComm
  • Language: English
  • DOI: 10.1039/c5md00245a
  • ISSN: 2040-2503; 2040-2511
  • Origination:
  • Footnote:
  • Description: <p>The thieno[2,3-<italic>b</italic>]pyridines bind to TDP1 with the best analogue <bold>9d</bold> with IC<sub>50</sub> at 0.5 μM.</p>