• Media type: E-Article
  • Title: Synthesis and evaluation of bis(imino)anthracene derivatives as G-quadruplex ligands
  • Contributor: Coban, Tomris; Robertson, Cameron; Schwikkard, Sianne; Singer, Richard; LeGresley, Adam
  • Published: Royal Society of Chemistry (RSC), 2021
  • Published in: RSC Medicinal Chemistry, 12 (2021) 5, Seite 751-757
  • Language: English
  • DOI: 10.1039/d0md00428f
  • ISSN: 2632-8682
  • Origination:
  • Footnote:
  • Description: The synthesis of a small number of bis(imino)anthracene derivatives is reported. They were evaluatedviaNMR for binding efficacy to the G-quadruplex-forming oligonucleotide sequence (TTGGGTT) and show activity against the HeLa cancer cell line.
  • Access State: Open Access