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Steinebach, Christian; Ng, Yuen Lam Dora; Sosič, Izidor; Lee, Chih-Shia; Chen, Sirui; Lindner, Stefanie; Vu, Lan Phuong; Bricelj, Aleša; Haschemi, Reza; Monschke, Marius; Steinwarz, Elisabeth; Wagner, Karl G.; Bendas, Gerd; Luo, Ji; Gütschow, Michael; Krönke, Jan

Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders

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  • Media type: E-Article
  • Title: Systematic exploration of different E3 ubiquitin ligases: an approach towards potent and selective CDK6 degraders
  • Contributor: Steinebach, Christian; Ng, Yuen Lam Dora; Sosič, Izidor; Lee, Chih-Shia; Chen, Sirui; Lindner, Stefanie; Vu, Lan Phuong; Bricelj, Aleša; Haschemi, Reza; Monschke, Marius; Steinwarz, Elisabeth; Wagner, Karl G.; Bendas, Gerd; Luo, Ji; Gütschow, Michael; Krönke, Jan
  • Published: Royal Society of Chemistry (RSC), 2020
  • Published in: Chemical Science, 11 (2020) 13, Seite 3474-3486
  • Language: English
  • DOI: 10.1039/d0sc00167h
  • ISSN: 2041-6520; 2041-6539
  • Origination:
  • Footnote:
  • Description: Cyclin-dependent kinase 6 (CDK6) is an important regulator of the cell cycle. Together with CDK4, it phosphorylates and inactivates retinoblastoma (Rb) protein.
  • Access State: Open Access