• Media type: E-Article
  • Title: Parallel mechanochemical optimization – Buchwald–Hartwig C–N coupling as a test case
  • Contributor: Lemesre, Quentin; Wiesner, Thomas; Wiechert, Rainer; Rodrigo, Eduardo; Triebel, Sonja; Geneste, Hervé
  • Published: Royal Society of Chemistry (RSC), 2022
  • Published in: Green Chemistry, 24 (2022) 14, Seite 5502-5507
  • Language: English
  • DOI: 10.1039/d2gc01460b
  • ISSN: 1463-9262; 1463-9270
  • Origination:
  • Footnote:
  • Description: Reaction conditions for mechanochemical Ar-amination were optimized in parallel: in a maximum of four steps [neat, LAG (water or methanol) and AG (sand) conditions] the yield could be significantly improved. The reaction time is short, and the conversion and purity are high.