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Darquenne, Chantal; Theilmann, Rebecca J.; Fine, Janelle M.; Verbanck, Sylvia A. B.

Nitrogen-based lung clearance index: a valid physiological biomarker for the clinic

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  • Media type: E-Article
  • Title: Nitrogen-based lung clearance index: a valid physiological biomarker for the clinic
  • Contributor: Darquenne, Chantal; Theilmann, Rebecca J.; Fine, Janelle M.; Verbanck, Sylvia A. B.
  • imprint: American Physiological Society, 2022
  • Published in: Journal of Applied Physiology
  • Language: English
  • DOI: 10.1152/japplphysiol.00511.2021
  • ISSN: 8750-7587; 1522-1601
  • Keywords: Physiology (medical) ; Physiology
  • Origination:
  • Footnote:
  • Description: <jats:p> The physiological content of N<jats:sub>2</jats:sub> multibreath washout testing has been questioned due to N<jats:sub>2</jats:sub> indirect measurement accuracy and N<jats:sub>2</jats:sub> blood solubility. With direct measurement of N<jats:sub>2</jats:sub> and twice as soluble argon, we show that these effects are largely outweighed by ease of use. </jats:p>
  • Access State: Open Access