• Media type: E-Article
  • Title: Synthesis of Some New Thiazole Derivatives and Their Biological Activity Evaluation
  • Contributor: Yurttaş, Leyla; Özkay, Yusuf; Karaca Gençer, Hülya; Acar, Ulviye
  • Published: Hindawi Limited, 2015
  • Published in: Journal of Chemistry
  • Extent: 1-7
  • Language: English
  • DOI: 10.1155/2015/464379
  • ISSN: 2090-9071; 2090-9063
  • Keywords: General Chemistry
  • Abstract: <jats:p>New 2-(4-arylpiperazine-1-yl)-<jats:italic>N</jats:italic>-[4-(2-(4-substituted phenyl)thiazol-4-yl)phenyl]acetamide derivatives were synthesized and evaluated for their antimicrobial and anticholinesterase activities. Acetylcholinesterase inhibitory activities of the compounds were found weak contrary to expectations. It is unlikely that antifungal activity of the compounds was found significant, especially against<jats:italic>Candida parapsilosis</jats:italic>.</jats:p>
  • Description: <jats:p>New 2-(4-arylpiperazine-1-yl)-<jats:italic>N</jats:italic>-[4-(2-(4-substituted phenyl)thiazol-4-yl)phenyl]acetamide derivatives were synthesized and evaluated for their antimicrobial and anticholinesterase activities. Acetylcholinesterase inhibitory activities of the compounds were found weak contrary to expectations. It is unlikely that antifungal activity of the compounds was found significant, especially against<jats:italic>Candida parapsilosis</jats:italic>.</jats:p>
  • Footnote:
  • Access State: Open Access