• Media type: E-Article
  • Title: Computed Tomography Findings of Pulmonary Mycobacterium simiae Infection
  • Contributor: Baghizadeh, Ayeh; Mehrian, Payam; Farnia, Poopak
  • imprint: Hindawi Limited, 2017
  • Published in: Canadian Respiratory Journal, 2017 (2017), Seite 1-5
  • Language: English
  • DOI: 10.1155/2017/6913564
  • ISSN: 1198-2241; 1916-7245
  • Keywords: Pulmonary and Respiratory Medicine
  • Origination:
  • Footnote:
  • Description: <jats:p>Nontuberculous mycobacterial (NTM) pulmonary infections can be quite similar to tuberculosis, both clinically and radiologically. However, the treatment protocol is not similar.<jats:italic> Mycobacterium simiae</jats:italic> is a rare cause of NTM pulmonary infection. Herein, we aimed to evaluate and compare the computed tomography (CT) scan findings of<jats:italic> M. simiae</jats:italic> infection in lungs. For this reason, thirty-four patients (<mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M1"><mml:mi>n</mml:mi><mml:mo>=</mml:mo><mml:mn fontstyle="italic">34</mml:mn></mml:math>) with<jats:italic> M. simiae</jats:italic> lung infection were retrospectively evaluated. Diagnosis was confirmed by American Thoracic Society (ATS) guidelines and CT scans were reviewed in both lung and mediastinal windows. The average age of patients was <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" id="M2"><mml:mn fontstyle="italic">63</mml:mn><mml:mo>±</mml:mo><mml:mn fontstyle="italic">14.54</mml:mn></mml:math> years and 52.9% were male. The majority of patients had cough (91.2%) and sputum production (76.5%). Clinically, 41.2% of patients had previous history of TB (14/34), 38.2% had cardiac diseases (13/34), and 35.3% had diabetes mellitus (12/34). The most common CT findings in our study were nodular lesions (100%) and bronchiectasis (85.29%). Regarding the severity, grade I bronchiectasis was the most prevalent. Other prominent findings were tree-in-bud sign (88.2%), consolidation (52.94%), and lobar fibrosis and volume loss (67.6%). There was no significant zonal distribution of findings. In conclusion, nodular lesions and bronchiectasis are the most frequent features in CT scan of<jats:italic> M. simiae</jats:italic> pulmonary infection.</jats:p>
  • Access State: Open Access