You can manage bookmarks using lists, please log in to your user account for this.
Media type:
E-Article
Title:
Laparoscopic Partial Hepatectomy in the Rat: A New Resectional Technique
Contributor:
Krähenbühl, Lukas;
Feodorovici, Michael;
Renzulli, Pietro;
Schäfer, Markus;
Abou-Shady, Mohamed;
Baer, Hans U.
Published:
S. Karger AG, 1998
Published in:
Digestive Surgery, 15 (1998) 2, Seite 140-144
Language:
English
DOI:
10.1159/000018607
ISSN:
0253-4886;
1421-9883
Origination:
Footnote:
Description:
<b>Background:</b> Rats are widely used for basic research in laparoscopic surgery. We have developed a new technique of laparoscopic partial hepatectomy in the rat. <b>Methods:</b> 40 American Cancer Institute rats were randomized into 3 groups. Group A (n = 14) underwent laparoscopic liver resection using a CO<sub>2</sub> pneumoperitoneum. Group B (n = 14) was operated on with a gasless laparoscopic technique using a lifting device. A control group C (n = 12) underwent conventional open liver resection. In each group half of the animals underwent single lobectomy and the other half bilobectomy. <b>Results:</b> The liver resection was performed successfully in all 40 rats. No conversion to open surgery was necessary. No mortality or morbidity was observed. <b>Conclusions:</b> This new technique of laparoscopic partial hepatectomy proved to be feasible and safe. It is the first description of a laparoscopic hepatic resection in the rat that could prove valuable in further investigations of liver physiology and pathology.