• Media type: E-Article
  • Title: Malignant Pleural/Pericardial Effusion with Tamponade and Life-Threatening Reversible Myocardial Depression in a Case of an Initial Presentation of Lung Adenocarcinoma
  • Contributor: Ma, Tony S.; Hayes, Teresa G.; Levine, Glenn N.; Carabello, Blase A.
  • Published: S. Karger AG, 2006
  • Published in: Cardiology, 105 (2006) 1, Seite 30-33
  • Language: English
  • DOI: 10.1159/000088344
  • ISSN: 1421-9751; 0008-6312
  • Origination:
  • Footnote:
  • Description: We present a case of a middle-aged woman in cardiac tamponade. Following pericardiocentesis that removed 1,500 ml of hemorrhagic fluid, the patient exhibited cardiogenic shock; LVEF, at its nadir, on inotrope, was less than 20%. Ventricular function slowly improved, with inotropic support, to the normal range by the 25th day of hospitalization. Cardiac failure in malignancy has often been attributed to multi-system failure; this case showed a hereto unrecognized clinical phenomenon – ‘malignancy-associated myopericarditis’. While the direct link of cause and effect cannot be made with certainty, the case should be instructive to other clinicians who encounter similar life-threatening presentations of cardiac decompensation in malignancy.