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Media type:
E-Article
Title:
Gastric Electrical Stimulation in Gastroparesis: Where Do We Stand?
Contributor:
Mönnikes, Hubert;
van der Voort, Ivo R.
Published:
S. Karger AG, 2006
Published in:
Digestive Diseases, 24 (2006) 3-4, Seite 260-266
Language:
English
DOI:
10.1159/000092879
ISSN:
1421-9875;
0257-2753
Origination:
Footnote:
Description:
Gastroparesis is a chronic disabling condition of impaired gastric motility that results in decreased quality of life. Currently available medical therapy consists of prokinetic and/or antiemetic therapy, dietary modifications, and nutritional supplementation. For patients with medication-resistant gastroparesis a non-pharmacological therapy, gastric electric stimulation, has evolved over the last decade. Based on the frequency of the electrical stimulus, gastric electric stimulation can be classified into low- and high-frequency gastric electric stimulation. The first method aims to normalize gastric dysrhythmia and entrain gastric slow waves and accelerates gastric emptying, whereas high-frequency gastric electric stimulation is unable to restore normal gastric emptying, but nevertheless stunningly reduces symptoms, such as nausea and vomiting, re-establishes quality of life, nutritional state in all patients, and metabolic control in patients with diabetic gastroparesis. Gastric electric stimulation presents a new possibility in the treatment of gastroparesis.