• Media type: E-Article
  • Title: Excimer Laser versus Narrow-Band UVB (311 nm) in the Treatment of Psoriasis Vulgaris
  • Contributor: Goldinger, Simone Maria; Dummer, Reinhard; Schmid, Peter; Prinz Vavricka, Mareike; Burg, Günter; Läuchli, Severin
  • imprint: S. Karger AG, 2006
  • Published in: Dermatology
  • Language: English
  • DOI: 10.1159/000093852
  • ISSN: 1018-8665; 1421-9832
  • Keywords: Dermatology
  • Origination:
  • Footnote:
  • Description: <jats:p>&lt;i&gt;Background:&lt;/i&gt; The excimer laser is a new therapeutic option in the treatment of psoriasis vulgaris. &lt;i&gt;Objective:&lt;/i&gt; The purpose of this study was to determine the response of psoriasis lesions to the 308-nm excimer laser compared to 311-nm UVB phototherapy. &lt;i&gt;Methods:&lt;/i&gt; In this prospective right/left comparative, open, single-blinded trial, selected psoriasis plaques of 16 patients were treated with the excimer laser whereas the rest of the body was treated with UVB narrow-band phototherapy. A modified PASI score was used to evaluate the results. &lt;i&gt;Results:&lt;/i&gt; After 12 treatments, 15 patients were evaluated. In 2 patients no difference between the two body sides was observed. In 9 patients the laser-treated lesions showed better results, whereas in 4 patients the side treated with 311-nm UVB showed more clearing. The mean reduction in PASI score was 5.6 and 4.9, respectively (difference not significant). &lt;i&gt;Conclusion:&lt;/i&gt; The use of the 308-nm xenon chloride excimer laser is an additional effective therapeutic option for the treatment of psoriasis vulgaris.</jats:p>