> Details

Castro-Varela, Alejandra; Martinez-Magallanes, Daniela M; Reyes-Chavez, Maria Fernanda; Gonzalez-Rayas, Jose Manuel; Paredes-Vazquez, Jose Gildardo; Vazquez-Garza, Eduardo; Castillo-Perez, Mauricio; Flores-Sayavedra, Yoezer Z; Martinez, Arturo; Ramos Cazares, Ray Erick; Guajardo, Jaime; Lopez-de la Garza, Hector; Salinas-Casanova, Jose Alfredo; Betancourt, Hector; Molina-Rodriguez, Abigail Montserrat; Panneflek, Jathniel; Fabiani, Mario Alejandro; Jerjes-Sanchez, Carlos

Risk Factors, Clinical Presentation, Therapeutic Trends, and Outcomes in Arterial Thrombosis Complicating Unvaccinated COVID-19 Patients: A Systematic Review

Reference
management

Bookmarks

Remove from
bookmarks

Share this on Whatsapp

Close

Bookmarks



You can manage bookmarks using lists, please log in to your user account for this.
  • Media type: E-Article
  • Title: Risk Factors, Clinical Presentation, Therapeutic Trends, and Outcomes in Arterial Thrombosis Complicating Unvaccinated COVID-19 Patients: A Systematic Review
  • Contributor: Castro-Varela, Alejandra; Martinez-Magallanes, Daniela M; Reyes-Chavez, Maria Fernanda; Gonzalez-Rayas, Jose Manuel; Paredes-Vazquez, Jose Gildardo; Vazquez-Garza, Eduardo; Castillo-Perez, Mauricio; Flores-Sayavedra, Yoezer Z; Martinez, Arturo; Ramos Cazares, Ray Erick; Guajardo, Jaime; Lopez-de la Garza, Hector; Salinas-Casanova, Jose Alfredo; Betancourt, Hector; Molina-Rodriguez, Abigail Montserrat; Panneflek, Jathniel; Fabiani, Mario Alejandro; Jerjes-Sanchez, Carlos
  • imprint: SAGE Publications, 2023
  • Published in: Angiology
  • Language: English
  • DOI: 10.1177/00033197231167055
  • ISSN: 1940-1574; 0003-3197
  • Keywords: Cardiology and Cardiovascular Medicine
  • Origination:
  • Footnote:
  • Description: <jats:p> Data on characteristics and outcomes of coronavirus (COVID)-19 patients complicated with arterial thrombosis (AT) are scarce. Therefore, we carried out a systematic review (PRISMA, PROSPERO statements; PubMed, Scopus, and Web of Science) to identify risk factors, clinical presentation, treatment, and outcomes. We included publications from December 2019 to October 2020. Groups: (a) ischemic stroke, (b) thrombotic storm, (c) peripheral vascular thrombosis, (d) myocardial infarction, and (e) left cardiac thrombus or in-transit thrombus (venous system thrombus floating or attaching to the right heart). We considered 131 studies. The most frequent cardiovascular risk factors were: hypertension, diabetes, and dyslipidemia. A high proportion presented with asymptomatic, mild, or moderate COVID-19 ( n = 91, 41.4%). We identified a high percentage of isolated ischemic stroke and thrombotic storm. Groups with higher mortality rate: intracardiac thrombus (1/2, 50.0%), thrombotic storm (18/49, 36.7%), and ischemic stroke (48/131, 36.6%). A small number received thromboprophylaxis. Most patients received antithrombotic treatment. The most frequent bleeding complication was intracranial hemorrhage, primarily with isolated stroke. Overall mortality was 33.6% (74/220). Despite a wide range of COVID-19 severity, a high proportion had AT as a complication of non-severe disease. AT can affect different vascular territories; mortality is associated with stroke, intensive care unit stay, and severe COVID-19. </jats:p>