• Media type: E-Article
  • Title: Surgical treatment of renal cell carcinoma with tumor thrombosis of the inferior vena cava and the right heart: How we do it
  • Contributor: Komarov, Roman N; Rapoport, Leonid M; Belov, Yuri V; Germagenova, Ekaterina K; Chernyavskii, Stanislav V; Ismailbaev, Alisher M; Tlisov, Boris M; Zhong, Baojun; Zavaruev, Artem V; Tsarichenko, Dmitry G; Korolev, Dmitry O
  • imprint: SAGE Publications, 2023
  • Published in: Urologia Journal
  • Language: English
  • DOI: 10.1177/03915603221143566
  • ISSN: 0391-5603; 1724-6075
  • Keywords: General Medicine
  • Origination:
  • Footnote:
  • Description: <jats:sec><jats:title>Objective:</jats:title><jats:p> Renal cell carcinoma with inferior vena cava thrombosis is a rare disease with a poor prognosis without surgical treatment. We report our 11-year experience in the surgical treatment of renal cell carcinoma with extension of the inferior vena cava. </jats:p></jats:sec><jats:sec><jats:title>Methods:</jats:title><jats:p> We conducted a retrospective analysis of patients undergoing surgical treatment for renal cell carcinoma with invasion of the inferior vena cava in two hospitals from May 2010 to March 2021. To assess the spread of the tumor process invasion, we used the Neves and Zincke classification. </jats:p></jats:sec><jats:sec><jats:title>Results:</jats:title><jats:p> A total of 25 people underwent surgical treatment. Sixteen patients were men, nine were women. Thirteen patients underwent cardiopulmonary bypass (CBP) surgery. The following postoperative complications were recorded: two cases of disseminate intravascular coagulation (DIC), two cases of acute myocardial infarction (MI) and one case of coma of unknown reason, Takotsubo syndrome and postoperative wound dehiscence. Three patients deceased (16.7%) of DIC syndrome and AMI. After discharge, one of the patients had a recurrence of tumor thrombosis 9 months after surgery, and another patient had the same 16 months later, presumably due to the neoplastic tissue in the adrenal gland on the contralateral side. </jats:p></jats:sec><jats:sec><jats:title>Conclusion:</jats:title><jats:p> We believe that this problem should be dealt with by an experienced surgeon with a multidisciplinary team in the clinic. The use of CPB provides benefits and reduces blood loss. </jats:p></jats:sec>