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Saxon, Cara J; Helbert, Matthew R; Komolafe, Adeniyi J; Higgins, Stephen P

Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both?

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  • Media type: E-Article
  • Title: Rash and hepatitis within days of starting a new antiretroviral regimen: nevirapine hypersensitivity, secondary syphilis or both?
  • Contributor: Saxon, Cara J; Helbert, Matthew R; Komolafe, Adeniyi J; Higgins, Stephen P
  • imprint: SAGE Publications, 2014
  • Published in: International Journal of STD & AIDS
  • Language: English
  • DOI: 10.1177/0956462413497703
  • ISSN: 0956-4624; 1758-1052
  • Keywords: Infectious Diseases ; Pharmacology (medical) ; Public Health, Environmental and Occupational Health ; Dermatology
  • Origination:
  • Footnote:
  • Description: <jats:p> We report a case in which an HIV-positive man developed general malaise, skin rash and biochemical hepatitis within days of starting a nevirapine-based antiretroviral treatment regimen. At the same time, his syphilis serology proved positive. We discuss the diagnostic dilemma: was this a nevirapine hypersensitivity reaction, secondary syphilis or both? </jats:p>