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Media type:
E-Article
Title:
Porcine Teschovirus Polioencephalomyelitis in Western Canada
Contributor:
Salles, Mônica W. S.;
Scholes, Sandra F. E.;
Dauber, Malte;
Strebelow, Günter;
Wojnarowicz, Chris;
Hassard, Lori;
Acton, Andy C.;
Bollinger, Trent K.
Published:
SAGE Publications, 2011
Published in:
Journal of Veterinary Diagnostic Investigation, 23 (2011) 2, Seite 367-373
Language:
English
DOI:
10.1177/104063871102300231
ISSN:
1040-6387;
1943-4936
Origination:
Footnote:
Description:
<jats:p> Beginning in 2002, a small number of pig farms in western Canada began reporting 4–7-week-old pigs with bilateral hind-end paresis or paralysis. Low numbers of pigs were affected, some died, most had to be euthanized, and those that survived had reduced weight gains and neurological deficits. Necropsies revealed no gross lesions, but microscopic lesions consisted of a nonsuppurative polioencephalomyelitis, most severe in the brain stem and spinal cord. The lesions were most consistent with a viral infection. Tests for circovirus, Porcine reproductive and respiratory syndrome virus, coronavirus, Rabies virus, and Pseudorabies virus were negative. Using immunohistochemistry, virus neutralization, fluorescent antibody test, and nested reverse transcription polymerase chain reaction, Porcine teschovirus was identified in tissues from affected individuals. To the authors' knowledge, this is the first report of teschovirus encephalitis in western Canada and the first reported case of polioencephalomyelitis in pigs in Canada, where teschovirus was confirmed as the cause. </jats:p>