• Media type: E-Article
  • Title: Antibacterial Potential of Citral Derivatives
  • Contributor: Singh, Soni A.; Potdar, Yogesh A.; Pawar, Rasika S.; Bhat, Sujata V.
  • imprint: SAGE Publications, 2011
  • Published in: Natural Product Communications
  • Language: English
  • DOI: 10.1177/1934578x1100600902
  • ISSN: 1934-578X; 1555-9475
  • Keywords: Complementary and alternative medicine ; Plant Science ; Drug Discovery ; Pharmacology ; General Medicine
  • Origination:
  • Footnote:
  • Description: <jats:p>Nine conjugated acid derivatives from monoterpene citral have been synthesized using ester, amide condensations, Wittig, Knoevenagel, Baylis-Hillman reactions and their antimicrobial activities were evaluated through disc diffusion and serial dilution methods. Several derivatives displayed interesting antimicrobial activity. Particularly, the Baylis-Hillman adducts 8-10 were found to have more potent antibacterial and antifungal activities than standard drugs namely chloramphenicol and nystatin respectively.</jats:p>
  • Access State: Open Access