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Media type:
E-Article
Title:
Contrast-enhanced ultrasound of breast tumors: an initial experience
Contributor:
Kristiansen, Merete U;
Martiniussen, Marit A;
Larsen, Anne Sofie F
imprint:
SAGE Publications, 2022
Published in:Acta Radiologica Open
Language:
English
DOI:
10.1177/20584601221097458
ISSN:
2058-4601
Origination:
Footnote:
Description:
<jats:sec><jats:title>Background</jats:title><jats:p> The increase of neoadjuvant treatment for breast cancer creates a capacity challenge as response evaluation by magnetic resonance imaging (MRI) is a limited resource. Contrast-enhanced ultrasound (CEUS) has been proposed as an alternative imaging strategy. </jats:p></jats:sec><jats:sec><jats:title>Purpose</jats:title><jats:p> To get experience with examination of malignant breast tumors with CEUS and evaluate the potential for future use in response evaluation of neoadjuvant treatment. </jats:p></jats:sec><jats:sec><jats:title>Material and methods</jats:title><jats:p> In this pilot study, the dynamic contrast-enhancement of ultrasound and MRI examinations were analyzed in 14 women with histologically verified breast cancer. </jats:p></jats:sec><jats:sec><jats:title>Results</jats:title><jats:p> Analysis of the time intensity curve of CEUS demonstrated the difference between tumor and normal tissue. The peak intensity was five times higher in tumor tissue (mean increase 397%, 95% CI 250–545). The curve was steeper for tumor tissue (mean 1.76, 95% CI 1.26–2.26) than for normal tissue (mean 0.43, 95% CI 0.24–0.62). </jats:p></jats:sec><jats:sec><jats:title>Conclusion</jats:title><jats:p> CEUS is a feasible method of examining blood flow in malignant breast tumors. </jats:p></jats:sec>